Proteins acting out of (dis)order
نویسنده
چکیده
A disordered region at the N-terminus of the glucocorticoid receptor can fine tune how cells respond to a hormone via an allosteric mechanism.
منابع مشابه
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The homeobox genes are known to play a crucial role in controlling the development of multicellular organisms. The majority of these genes have been determined to express regulatory proteins act as a regulatory protein. These trans-acting factors regulate the expression of proteins that are necessary during the developmental processes throughout the body. TGIFLX/Y is a homeobox gene and it cont...
متن کاملبررسی روایی و پایایی نسخه فارسی پرسشنامه «کیفیت زندگی افراد ناتوان سازمان بهداشت جهانی» (WHOQOL-DIS) در افراد سالمند ناتوان
Objective: The main purpose of the present study was to evaluate psychometric properties of Persian version of WHOQOL-DIS questionnaire in elderly people with disability. Materials & Methods A classical psychometric method was used to evaluate validity and reliability of WHOQOL-DIS questionnaire in elderly people with disability. Lawshe, and Waltz and Bausell methods were used for assessing ...
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The features of Helicobacter pylori adhesins, their interactions with their host counterparts, regulated and selective gene expressions are amongst the many clever strategies this microorganism undertakes to survive the otherwise sterile gastric milieu. The ingenious crafting of these interactions and the respective host reactions govern, in part, an array of consequences ranging from asympto...
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Generalized Parton Distributions (GPDs) provide information on the distribution of quarks in impact paarmeter space. For transversely polarized nucleons, these impact parameter distributions are transversely distorted and this deviation from axial symmetry leads on average to a net transverse force from the spectators on the active quark in a DIS experiment. This force when acting along the who...
متن کاملDetermining the frequency and mechanisms of HIV-1 and HIV-2 RNA copackaging by single-virion analysis.
HIV-1 and HIV-2 are derived from two distinct primate viruses and share only limited sequence identity. Despite this, HIV-1 and HIV-2 Gag polyproteins can coassemble into the same particle and their genomes can undergo recombination, albeit at an extremely low frequency, implying that HIV-1 and HIV-2 RNA can be copackaged into the same particle. To determine the frequency of HIV-1 and HIV-2 RNA...
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